Human DNA Deoxyribonucleic acid (DNA) is a molecule that encodes an organism’s genetic blueprint. In other words, DNA contains all of the information required to build and maintain an organism. DNA was discovered in 1868, when twenty-four-year-old Swiss physician Friedrich Miescher isolated a compound from the nuclei of white blood cells. This compound was neither a protein nor a lipid nor a carbohydrate, so it was therefore a novel type of biological molecule. Miescher named his discovery “nuclein,” because he had isolated it from the nuclei of cells. Today, this molecule is called DNA. Nearly all of the cells within a single organism include exactly the same DNA#DeoxyriboNucleicAcid, #DNA -Read More Here:http://stemcellthailand.org/dna/

Human DNA

Deoxyribonucleic acid (DNA) is a molecule that encodes an organism’s genetic blueprint. In other words, DNA contains all of the information required to build and maintain an organism. DNA was discovered in 1868, when twenty-four-year-old Swiss physician Friedrich Miescher isolated a compound from the nuclei of white blood cells. This compound was neither a protein nor a lipid nor a carbohydrate, so it was therefore a novel type of biological molecule. Miescher named his discovery “nuclein,” because he had isolated it from the nuclei of cells. Today, this molecule is called DNA. Nearly all of the cells within a single organism include exactly the same DNA

#DeoxyriboNucleicAcid, #DNA -Read More Here:http://stemcellthailand.org/dna/
Cell replacement to treat ParkinsonsTransplanted cells can flourish for over a decade in the brain of a person with Parkinson’s disease..he five had received stem cell transplants between four and 14 years earlier. In all five people’s samples, neurons that originated from the transplanted cells showed signs of good health and appeared capable of sending messages with the brain chemical dopamine, a neurotransmitter that Parkinson’s depletes.   -Read More Here:http://wp.me/P2CnW0-AW

Cell replacement to treat Parkinsons

Transplanted cells can flourish for over a decade in the brain of a person with Parkinson’s disease..he five had received stem cell transplants between four and 14 years earlier. In all five people’s samples, neurons that originated from the transplanted cells showed signs of good health and appeared capable of sending messages with the brain chemical dopamine, a neurotransmitter that Parkinson’s depletes.

-Read More Here:http://wp.me/P2CnW0-AW
Scientists have regrown cornea tissue using Stem CellsLimbal stem cells can be found in the eye’s basal limbal epithelium, or limbus, and assist handle and regenerate corneal tissue. Their loss due to injury or disease is likely one of the best motives of blindness. previously, tissue or cell transplants had been used to lend a hand the cornea regenerate, but it was unknown whether or not there have been exact limbal stem cells in the grafts, or how many, and the results weren’t constant.#ABCB5, #CureBlindness, #LimbalStemCells -Read More Here:http://wp.me/p2CnW0-AN

Scientists have regrown cornea tissue using Stem Cells

Limbal stem cells can be found in the eye’s basal limbal epithelium, or limbus, and assist handle and regenerate corneal tissue. Their loss due to injury or disease is likely one of the best motives of blindness. previously, tissue or cell transplants had been used to lend a hand the cornea regenerate, but it was unknown whether or not there have been exact limbal stem cells in the grafts, or how many, and the results weren’t constant.

#ABCB5, #CureBlindness, #LimbalStemCells -Read More Here:http://wp.me/p2CnW0-AN
Function of Stromal CellsCertain types of basal cell carcinomas (skin Cancers) cannot spread throughout the body because the cancer cells require nearby stromal cells to continue their division. The loss of these stromal growth factors when the cancer moves throughout the body prevents the cancer from invading other organs.#MesenchymalStromalCells, #StromalCells -Read More Here:http://wp.me/p2CnW0-AB

Function of Stromal Cells

Certain types of basal cell carcinomas (skin Cancers) cannot spread throughout the body because the cancer cells require nearby stromal cells to continue their division. The loss of these stromal growth factors when the cancer moves throughout the body prevents the cancer from invading other organs.

#MesenchymalStromalCells, #StromalCells -Read More Here:http://wp.me/p2CnW0-AB
Relieve Sciatica Without Back Surgery And Steroid InjectionsMany people with sciatica do not want to resort to surgery or risk the side effects associated with steroid injections. Regeneration Center of Thailand offers an effective, non-invasive alternative to surgery and steroid injections for sciatica. Our same-day in office procedure treats the underlying issue causing your pain utilizing stem cell therapy, Our advanced form of platelet rich plasma (PRP) therapy, and other regenerative procedures. -Read More Here:http://wp.me/P2CnW0-A6

Relieve Sciatica Without Back Surgery And Steroid Injections

Many people with sciatica do not want to resort to surgery or risk the side effects associated with steroid injections. Regeneration Center of Thailand offers an effective, non-invasive alternative to surgery and steroid injections for sciatica. Our same-day in office procedure treats the underlying issue causing your pain utilizing stem cell therapy, Our advanced form of platelet rich plasma (PRP) therapy, and other regenerative procedures.

-Read More Here:http://wp.me/P2CnW0-A6
Mesoderm Development Extraembryonic IntraembryonicMesoderm is the The middle part of the three germ layers and a derivative of a blastocyst inner cell mass. The mesodermal layer is composed of cells that have the ability to differentiate into muscle and bone cells, as well as kidney cells ,ligaments and connective tissues.

For humans, …#Mesoderm -Read More Here:http://wp.me/p2CnW0-zp

Mesoderm Development Extraembryonic Intraembryonic

Mesoderm is the The middle part of the three germ layers and a derivative of a blastocyst inner cell mass. The mesodermal layer is composed of cells that have the ability to differentiate into muscle and bone cells, as well as kidney cells ,ligaments and connective tissues. For humans, …

#Mesoderm -Read More Here:http://wp.me/p2CnW0-zp
Induced Pluripotent Cells iPS cells vs Embryonic stem cells Induced Pluripotent Cells or “IPS” cells and embryonic stem cells are very similar. They are self-renewing, meaning they can divide and produce copies of themselves indefinitely. Both types of stem cell can be used to derive nearly any kind of specialized cell under precisely controlled conditions in the laboratory. Both iPS cells and embryonic stem cells can help us understand how specialized cells develop from pluripotent cells. In the future, they might also provide an unlimited supply of replacement cells and tissues for many patients with currently untreatable diseases.#InducedPluripotentStemCells, #IPS -Read More Here:http://wp.me/p2CnW0-z8

Induced Pluripotent Cells iPS cells vs Embryonic stem cells

Induced Pluripotent Cells or “IPS” cells and embryonic stem cells are very similar. They are self-renewing, meaning they can divide and produce copies of themselves indefinitely. Both types of stem cell can be used to derive nearly any kind of specialized cell under precisely controlled conditions in the laboratory. Both iPS cells and embryonic stem cells can help us understand how specialized cells develop from pluripotent cells. In the future, they might also provide an unlimited supply of replacement cells and tissues for many patients with currently untreatable diseases.

#InducedPluripotentStemCells, #IPS -Read More Here:http://wp.me/p2CnW0-z8
Homing or Cell Migration in Stem Cell Therapies - http://wp.me/p2CnW0-yM #GlossaryHematopoietic stem cells (HSC) are a population of precursor cells that posses the capacity for self-renewal and multilineage differentiation. In the bone marrow (BM), HSCs warrant blood cell homeostasis, but at the same time a stable pool of functional cells must be constantly maintained. For this, HSCs constitute a model in which subpopulations of quiescent and active adult stem cells co-exist in the same tissue, in specific microenvironment called stem-cell “niches.” These microenvironments keep the stem cells at quiescent (osteoblastic niche) for its self-renewal and activate the stem cells (vascular niche) for proliferation and/or injury repair, maintaining a dynamic balance between self-renewal and differentiation. HSC reside in the bone marrow but can be forces into the blood, a process termed mobilization used clinically to harvest large number of cells for transplantation. At the same time, homing to the BM is necessary to optimize cell engraftment. Here, we summarize current understanding of HSC niche characteristics, and the physiological and pathological mechanisms that guide HSC mobilization both within the BM and to distant niches in the periphery. Mobilization and Homing are mirror process depending on an interplay between chemokines, chemokine receptors, intracellular signaling, adhesion moleculas and proteases. The interaction between SDF-1/CXCL12 and its receptor CXCR4 is critical to retain HSCs within the bone marrow. Current mobilization strategies used in clinic, mainly G-CSF cytokine, are well tolerated but often produce suboptimal number of collected HSCs. Novel agents (AMD3100, stem cell factor, GROßT.) are being developed to enhance the mobilization to modify the signaling into the niche and boost the stem cell harvest, increasing the number of HSCs available for the transplant.#CellMigration, #Homing -Read More Here:http://wp.me/p2CnW0-yM

Homing or Cell Migration in Stem Cell Therapies - http://wp.me/p2CnW0-yM #Glossary

Hematopoietic stem cells (HSC) are a population of precursor cells that posses the capacity for self-renewal and multilineage differentiation. In the bone marrow (BM), HSCs warrant blood cell homeostasis, but at the same time a stable pool of functional cells must be constantly maintained. For this, HSCs constitute a model in which subpopulations of quiescent and active adult stem cells co-exist in the same tissue, in specific microenvironment called stem-cell “niches.” These microenvironments keep the stem cells at quiescent (osteoblastic niche) for its self-renewal and activate the stem cells (vascular niche) for proliferation and/or injury repair, maintaining a dynamic balance between self-renewal and differentiation. HSC reside in the bone marrow but can be forces into the blood, a process termed mobilization used clinically to harvest large number of cells for transplantation. At the same time, homing to the BM is necessary to optimize cell engraftment. Here, we summarize current understanding of HSC niche characteristics, and the physiological and pathological mechanisms that guide HSC mobilization both within the BM and to distant niches in the periphery. Mobilization and Homing are mirror process depending on an interplay between chemokines, chemokine receptors, intracellular signaling, adhesion moleculas and proteases. The interaction between SDF-1/CXCL12 and its receptor CXCR4 is critical to retain HSCs within the bone marrow. Current mobilization strategies used in clinic, mainly G-CSF cytokine, are well tolerated but often produce suboptimal number of collected HSCs. Novel agents (AMD3100, stem cell factor, GROßT.) are being developed to enhance the mobilization to modify the signaling into the niche and boost the stem cell harvest, increasing the number of HSCs available for the transplant.

#CellMigration, #Homing -Read More Here:http://wp.me/p2CnW0-yM
Cancer Stem Cells Cancer stem cells (CSCs) pertain to cancer cells usually found in hematologic cancers or tumors having the specific characteristics of regular stem cells. They normally have the specific capability of self-renewal and can transform into other types of cells like neural cells,skin cells,tissue…#CancerStemCells -Read More Here:http://wp.me/p2CnW0-yB

Cancer Stem Cells

Cancer stem cells (CSCs) pertain to cancer cells usually found in hematologic cancers or tumors having the specific characteristics of regular stem cells. They normally have the specific capability of self-renewal and can transform into other types of cells like neural cells,skin cells,tissue…

#CancerStemCells -Read More Here:http://wp.me/p2CnW0-yB